HCCcare is an educational resource tool that was developed to support Canadian medical oncologists in selecting the most appropriate first line systemic therapy for patients with hepatocellular carcinoma (HCC), based on current drug approvals. With HCCcare, clinicians can review systemic treatment considerations, treatment logistics, patient support programs, and clinical trial summaries all in one place. The content for HCCcare was developed by a Scientific Planning Committee of key opinion leaders and clinicians in the field of HCC.